Cystic fibrosis in the 21st century

Ch. 1. The CFTR gene : structure, mutations and specific therapeutic approaches / M. Nissim-Rafinia, L. Linde and B. Kerem

Ch. 2. Exquisite and multilevel regulation of CFTR expression / A. E. O. Trezise

Ch. 3. Intracellular processing of CFTR / H. Barriere and G. L. Lukacs

Ch. 4. Structure of the cystic fibrosis transmembrane conductance regulator / F. L. L. Stratford and C. E. Bear

Ch. 5. Function of CFTR protein : ion transport / J.-H. Chen, Z. Cai, H. Li and D. N. Sheppard

Ch. 6. Cystic fibrosis : function of CFTR protein : regulatory functions / R. D. Coakley and M. J. Stutts

Ch. 7. Function of CFTR protein : developmental role / D. Gill and J. E. Larson

Ch. 8. Genotype-phenotype correlations in cystic fibrosis / R. Dorfman and J. Zielenski

Ch. 9. Diagnosis of cystic fibrosis, CFTR-related disease and screening / B. A. Karczeski and G. R. Cutting

Ch. 10. CF modifier genes / U. Griesenbach, E. W. F. W. Alton and J. C. Davies

Ch. 11. Animal models / J. R. Dorin

Ch. 12. In vitro/ex vivo fluorescence assays of CFTR chloride channel function / A. S. Verkman and L. J. V. Galietta

Ch. 13. In vivo measurement of airway potential difference to assess CFTR function in man / P. Middleton and E. W. F. W. Alton

Ch. 14. Arrays and proteomics / V. C. Ogilvie and G. MacGregor

Ch. 15. Pathogenesis of pulmonary disease in cystic fibrosis / M. Mall and R. C. Boucher

Ch. 16. Infection versus inflammation / A. G. Ziady and P. B. Davis

Ch. 17. Pseudomonas aeruginosa : clinical research / D. Armstrong

Ch. 18. Pseudomonas aeruginosa : basic research / F. W. Scott and T. L. Pitt

Ch. 19. Other gram-negative organisms : Burkholderia cepacia complex and Stenotrophomonas maltophilia / J. R. W. Govan

Ch. 20. Staphylococcus aureus and MRSA / S. Conway and M. Denton

Ch. 21. Nontuberculous mycobacterial lung disease in patients with cystic fibrosis / D. E. Griffith

Ch. 22. Respiratory fungal infections and allergic bronchopulmonary aspergillosis / C. Que and D. Geddes

Ch. 23. Advanced disease management and advances in transplant medicine / M. R. Carby and M. E. Hodson

Ch. 24. Current and novel antimicrobial approaches / J. C. Davies

Ch. 25. Anti-inflammatory agents : a clinical perspective / T. N. Hilliard and I. M. Balfour-Lynn

Ch. 26. Recent advances in infant and pre-school lung function / S. Ranganathan

Ch. 27. Recent advances in imaging / A. Oikonomou and D. M. Hansell

Ch. 28. New pharmacological approaches for treatment of cystic fibrosis / R. C. Rubenstein

Ch. 29. Gene and stem cell therapy / A. C. Boyd

Ch. 30. Gut disease : clinical manifestations, pathophysiology, current and new treatments / C. J. Taylor and J. Hardcastle

Ch. 31. Pancreatic involvement : clinical manifestations, pathophysiology and new treatments / K. J. Lindley

Ch. 32. Cystic fibrosis : liver disease / D. Westaby

Ch. 33. Fertility, contraception, incontinence and pregnancy / J. G. Thorpe-Beeston

Ch. 34. Arthritis, vasculitis and bone disease / S. Elkin

Ch. 35. Diabetes in cystic fibrosis / N. Bridges and K. Spowart

Ch. 36. Challenges for nurses / S. Madge

Ch. 37. Dietetics / S. Wolfe and A. Morton

Ch. 38. Physiotherapy / J. A. Pryor, E. Main, P. Agent and J. M. Bradley

Ch. 39. Psychological interventions / M. Bryon

Ch. 40. The future / A. Bush, U. Griesenbach, J. C. Davies, E. W. F. W. Alton and A. Jaffe