Epigenetics in Biology and MedicineManel Esteller CRC Press, 17 sept 2008 - 312 páginas Anomalous epigenetic patterns touch many areas of study including biomedical, scientific, and industrial. With perspectives from international experts, this resource offers an all-inclusive overview of epigenetics, which bridge DNA information and function by regulating gene expression without modifying the DNA sequence itself. Epigenetics, in its |
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17 | |
27 | |
49 | |
Sirtuins in Biology and Disease | 73 |
microRNAs in Cell Biology and Diseases | 105 |
Chromatin Modifications by Polycomb Complexes | 131 |
Epigenetics and its Genetic Syndromes | 155 |
Epigenetics and Immunity | 175 |
Etiology of Major Psychosis Why Do We Need Epigenetics? | 189 |
Epigenetics and Cardiovascular Disease | 207 |
Plant Epigenetics | 225 |
Epigenetics Environment and Evolution | 241 |
Epigenetics and Epigenomics | 261 |
285 | |
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5-aza-2′-deoxycytidine 5-azacytidine acetylation acid activity apoptosis associated binding Biol Biology cancer cells Cancer Res cell cycle cell lines cellular Chem chromatin chromosome Clin complex CpG islands deacetylation demethylation detected differentiation disease DNA hypomethylation DNA methylation DNA methyltransferase DNA repair domain Drosophila effects enzymes epigenetic changes epigenome Ezh2 function gene expression Genet genome genome-wide global HDACi HDACs heterochromatin histone deacetylase histone H3 histone modifications human cancer identified inactivation increase induced inhibition inhibitors interaction involved leukemia levels lifespan lupus lymphoma lysine mammalian mechanisms MeCP2 mice microarray microRNAs miRNAs molecular mutations myelodysplastic syndrome Natl Acad Sci normal Oncogene Oncol overexpression pathway patients patterns phase phenotype plants Polycomb group Proc Natl Acad promoter protein receptor regions regulation regulatory repression response role schizophrenia silencing Sir2 SirT1 SirT2 SirT3 sirtuins specific stem cells subunits target tion tissues transcription factors tumor suppressor unmethylated upregulated yeast