The Human Genome Project: How Private Sector Developments Affect the Government Program : Hearing Before the Subcommittee on Energy and Environment of the Committee on Science, U.S. House of Representatives, One Hundred Fifth Congress, Second Session, June 17, 1998, Volumen 4U.S. Government Printing Office, 1998 - 429 páginas |
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acid Alamos analysis approach automated base pairs Biological and Environmental biotechnology cDNA cells chromo chromosome 19 clones collaboration complete contig map contigs cosmid Craig Venter detection developed disease DNA fragments DNA sequence DOE and NIH DOE Grant DOE Human Genome donors ELSI Environmental Research enzyme federal fluorescence function funding genes genetic information goal GSDB Health human chromosome Human Genome Center Human Genome Program Human Genome Project human genome sequencing hybridization identified informatics initial Institute issues Joint Genome Institute LANL large-scale sequencing Lawrence Livermore National libraries Livermore National Laboratory LLNL mapping and sequencing markers ment methods Molecular mouse nome nucleotide Oak Ridge oligonucleotides organisms patent Perkin-Elmer physical map polymerase primer probes production protein quence regions samples Science scientific scientists sector sequence data sequence tagged site shotgun specific strategy tion University
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Página 416 - California nor any of their employees, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information, apparatus, product, or process disclosed, or represents that its use would not infringe privately owned rights. Reference herein to any specific commercial...
Página 12 - J. Antsaklis received his Diploma in Mechanical and Electrical Engineering from the National Technical University of Athens, Greece in 1972 and his M.Sc and Ph.D in Electrical Engineering from Brown University, Providence, RI in 1974 and 1977, respectively.
Página 253 - Gene: The fundamental physical and functional unit of heredity. A gene is an ordered sequence of nucleotides located in a particular position on a particular chromosome that encodes a specific functional product (ie, a protein or RNA molecule).
Página 12 - Co-Chairman of the Committee on Environment and Natural Resources of the National Science and Technology Council and as an ex-officio member of the President's Council on Sustainable Development.
Página 67 - Burke, DT, Carle, GF, and Olson, MV (1987) Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors.
Página 255 - Physical map A map of the locations of identifiable landmarks on DNA (eg, restriction -enzyme cutting sites, genes), regardless of inheritance. Distance is measured in base pairs. For the human genome, the lowest-resolution physical map is the banding patterns on the 24 different chromosomes; the highest-resolution map is the complete nucleotide sequence of the chromosomes.
Página 257 - Transfer RNA (tRNA): A class of RNA having structures with triplet nucleotide sequences that are complementary to the triplet nucleotide coding sequences of mRNA. The role of tRNAs in protein synthesis is to...
Página 257 - RNA (Ribonucleic acid) A chemical found in the nucleus and cytoplasm of cells; it plays an important role in protein synthesis and other chemical activities of the cell. The structure of RNA is similar to that of DNA. There are several classes of RNA molecules, including messenger RNA, transfer RNA, ribosomal RNA, and other small RNAs, each serving a different purpose.