Familial Cancer and Prevention: Molecular Epidemiology: A New Strategy Toward Cancer Control

Portada
Joji Utsunomiya, John J. Mulvihill, Walter Weber
John Wiley & Sons, 27 abr. 1999 - 559 páginas
A New Strategy Toward Cancer Control.

Still in its infancy, the familial/hereditary approach to cancer control is proving to be one of the most potent strategies in the war on cancer. Over the past few years the human genome project has generated an abundance of valuable information on the genetic origins of a range of cancers. Tests now exist for several hereditary, tumor-promoting genetic mutations-including those found in BRCA genes associated with breast cancer as well as mutations of HNPCC genes which have been linked to colon cancers-and many more are anticipated in the near future. Armed with the information yielded by these tests, physicians have already saved countless lives through preventative counseling, early detection, and more highly-focused intervention strategies.

Inspired by the proceedings of the UICC 1997 Symposium on Familial Cancer and Prevention held in Kobe, Japan, this volume provides clinicians and researchers with a detailed review of the latest developments at the front lines of the familial cancer prevention movement. In a series of edited contributions, leading researchers and clinicians from around the globe summarize their experiences and analyze current and emerging trends in:
* Information gathering and history taking.
* Risk assessment.
* Genetic testing for colorectal, endocrine, breast, and other familial cancers.
* Diagnosis, prognosis, and management of an array of familial cancers.
* Genetic counseling for familial cancers.

Up-to-date, authoritative, and comprehensive, Familial Cancer and Prevention is an important working resource for clinicians, cancer researchers, and epidemiologists.
 

Comentarios de usuarios - Escribir una reseña

No hemos encontrado ninguna reseña en los sitios habituales.

Índice

Introduction
3
Molecular Epidemiology of Human Cancer
16
The Rationale of a Questionnaire
23
ObjectOriented Computer Software Linking a Pedigree Drawing
35
Research and Clinical Care Networks in Neurofibromatosis
43
Experience of the First
51
Family HistoryBased Screening for Colorectal Cancer
59
Characteristics of 552 Consultees
65
Genetic Diagnosis and Management of Suspected Hereditary
267
Prevention
273
A Trial of Aspirin andor
279
Dietary Prevention of Colorectal Cancer
285
Calcium in Cancer Prevention
291
Phase III MultipleDose Safety and Efficacy Clinical
303
The Impact of Living With Hereditary Colorectal Disease
315
The Tata Memorial
321

Efficacy of a Clinical Risk
71
Hereditary Tumor Registry in Korea
77
The Parallel With
83
Clinical
89
A Nursing Perspective of Counseling Families in a Cancer
105
The Nurses Role in Decision Making in Familial Cancer
111
New and Evolving Challenges for Oncology
117
Genetic Counseling and Its Ethical Issues in Japan
131
Bioethical Concerns With Rights of Patients Receiving
137
Use of Genetic Information by Private Insurers
143
Familial Adenomatous Polyposis
153
Extracolonic Symptoms of Familial Adenomatous Polyposis
163
Desmoid Disease in Familial Adenomatous Polyposis
171
Chemoprevention of Colorectal Adenomas in Familial
177
Interventional Trial for Cancer Prevention for Familial
191
Colorectal Cancer Prognosis in Hereditary Nonpolyposis
207
Evolution of Neoplasia in Hereditary Nonpolyposis
215
Controversial Issues in Hereditary Nonpolyposis Colorectal Cancer
221
Benign Extracolonic Manifestations Associated With Hereditary
227
An Automated Genetic Assay for Hereditary Nonpolyposis
245
Complex Genetic Predisposition to Cancer in an Extended
251
Surveillance and Management of Hereditary Nonpolyposis
259
GeneDiet Interactions and the High Colorectal Cancer Risk
329
Impact of Migration on the Phenotypes of Familial Cancer
337
Mutagen Sensitivity as a Predisposing Factor in the Identification
345
Genetic Alterations in Esophageal Cancers
353
Identification and Characterization of Families With Aggregation
361
Inherited Medullary Thyroid Carcinoma in Japan
371
Management of Hereditary Medullary Thyroid Carcinoma
377
Consequences of Specific RET Gene Mutations in Families With
385
Recurrent Loss of Heterozygosity for Chromosome 1p in Siblings
393
Recent Developments in the Genetic Epidemiology of Breast Cancer
401
Mapping of NonBRCA12 Breast Cancer Genes
409
Clinical Morphological
419
A Novel 150K Marker for Early Human Mammary Carcinoma
425
Endocrine Approaches to Breast Cancer Prevention
431
DNABased Genetic Counseling
441
Case Series Compared
449
Progress in the Diagnosis and Management of Neurofibromatosis
455
Cancer Genetics of the Tuberous Sclerosis TSC2 Gene Mutant
475
Cutaneous Malignant Melanoma
493
Adult Progeria With CancerProne Inheritance
507
UICC Molecular Biology Workshop Report
525
Página de créditos

Otras ediciones - Ver todo

Términos y frases comunes

Pasajes populares

Página 506 - Prevention of skin cancer in xeroderma pigmentosum with the use of oral isotretinoin, N. Engl. J. Med., 318, 1633, 1988.

Sobre el autor (1999)

Joji Utsunomiya and John J. Mulvihill are the authors of Familial Cancer and Prevention: Molecular Epidemiology: A New Strategy Toward Cancer Control, published by Wiley.

Información bibliográfica