Copper and Zinc in Inflammatory and Degenerative DiseasesK. D. Rainsford, Roberto Milanino, J.R.J. Sorenson, G. P. Velo Springer Science & Business Media, 28 feb 1998 - 197 páginas Abnormal metabolism and distribution of both copper and zinc occurs in many inflammatory and degenerative diseases. The pattern of these changes varies at different stages of these diseases and with differing types of conditions. The corollary to this situation is the possibility of using drugs or metal complexes to modify both the perturbed status of copper and zinc and thus the disease states. This book comprehensively reviews the clinical and experimental data on the changes in copper and zinc status in different diseases and the use of various complexes of these metals or drugs to treat a diversity of inflammatory and degenerative conditions. |
Índice
History of zinc therapy | 1 |
Physiological properties of copper and zinc | 7 |
Biological chemistry of copper compounds | 19 |
The biological chemistry of zinc | 47 |
Copper and zinc metallothioneins | 61 |
Zinc in the regulation and therapy of inflammatory diseases and gastrointestinal ulceration | 79 |
Copper complexes for therapy of cancer and autoimmune diseases | 113 |
8 Zinc and copper in the treatment of rheumatic diseases | 125 |
9 Topically applied copper preparations for antiinflammatory therapy | 139 |
Regulation by copper of rat adjuvantarthritis a model of chronic inflammation especially suitable for studying the mechanisms of copper antiinflamm... | 147 |
Copper and zinc compounds and cell surface interactions | 161 |
12 Copper and postmenopausal osteoporosis | 173 |
Menkes disease a genetic defect of copper transport | 179 |
| 189 | |
Otras ediciones - Ver todo
Copper and Zinc in Inflammatory and Degenerative Diseases K. D. Rainsford,Roberto Milanino,J.R.J. Sorenson,G.P Velo Vista previa restringida - 2012 |
Copper and Zinc in Inflammatory and Degenerative Diseases K. D. Rainsford,Roberto Milanino,J.R.J. Sorenson,G. P. Velo No hay ninguna vista previa disponible - 2012 |
Copper and Zinc in Inflammatory and Degenerative Diseases K. D. Rainsford,Roberto Milanino,J.R.J. Sorenson,G. P. Velo No hay ninguna vista previa disponible - 2011 |
Términos y frases comunes
absorption adhesion albumin Alzheimer's disease apoptosis binding Biol biological Biophys blood bone bucillamine catalytic cells cellular ceruloplasmin chelates Chem Chemistry chondrocytes cimetidine Clin clinical co-ordination concentrations copper and zinc copper chelates copper complexes copper deficiency copper proteins copper salicylate copper-histidine copper(II Cu-PuPy Cu(II cytokines diet dietary drugs effects of zinc enzymes excretion function gastric gene glutathione human immune increased induced inflammation inflammatory inhibition interactions intestinal intracellular Kluwer Academic Publishers levels ligands liver lymphocytes mechanisms Menkes disease metabolism metal ions metallothionein Milanino modulation molecular molecules mucosal normal NSAIDs Nutr osteoporosis oxidase oxide oxygen peroxide Pharmacol physiological plasma zinc protein Rainsford KD rats receptor redox reduced regulation reported response rheumatoid arthritis salicylate serum Sorenson JRJ stability structure studies superoxide dismutase synthesis therapy tissue Trace Elements transport treatment Weser Whitehouse MW zinc compounds zinc deficiency zinc ions zinc status zinc sulphate zinc supplementation Zn2+ µmol/L