Childhood LeukemiasChing-Hon Pui Cambridge University Press, 13 ago 1999 - 567 páginas Childhood leukemias represent nearly one third of all cancers in children and present a unique challenge to oncologists, pediatricians, hematologists, and other health professionals. Dr Ching-Hon Pui has assembled an expert team of authors to develop the most comprehensive, clinically-oriented, and authoritative reference dedicated to these diseases. Childhood Leukemias moves from the laboratory bench to the patient bedside in three easily-accessible sections. Part one presents an in-depth review of topics needed to understand the pathobiology of leukemia. Part two builds upon this scientific foundation by explaining practical approaches to clinical diagnosis, evaluation, and treatment. The final section outlines major clinical complications which arise during and after treatment. Chapters on supportive care, psychosocial issues, and nursing will also interest general practitioners and nurses. The entire text is supplemented by numerous tables and figures. Fully referenced and up-to-date, Childhood Leukemias is an absolute 'must-have' for any physician or investigator who deals with leukemias in childhood. |
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abnormalities Acad Sci USA acid activity acute leukemia acute lym acute lymphoblastic leukemia acute myeloid leukemia acute promyelocytic leukemia allogeneic analysis antibodies antigen apoptosis assay associated B-lineage binding blast cells Blood bone marrow transplantation Cancer cell lines chemotherapy childhood acute lymphoblastic childhood leukemia children with acute chromosomal translocations chromosome chronic Clin Oncol clinical clonal cytogenetic cytokines detection diagnosis differentiation domain donor drug encodes Engl erythroid expression function fusion G-CSF gene rearrangements gene segments genetic granulocytic Haematol hematopoietic cells human immunoglobulin immunophenotype induced infection kinase leukemic cells lineage lymphocytes lymphoid lymphoma malignancies methotrexate mice molecular myelodysplastic syndrome Natl Acad Sci normal Oncogene patients Pediatric Oncology Group phenotype phoblastic leukemia platelet pre-B Proc Natl Acad progenitors prognostic protein Pui C-H Raimondi SC receptor relapse remission risk specific stem cells studies subtype syndrome T-cell target TCR gene therapy tion transcription translocation treatment tumor vitro