Principles of Forensic Toxicology

absorbed absorption abuse acid active administration alcohol amine amphetamine analgesic analysis analyte antibodies antidepressants antipsychotic assay barbiturates behavior benzodiazepines benzoylecgonine binding brain cannabinoids cause centrations chemical chromatography chronic clinical clozapine cocaine codeine COHb column compounds concen cross-reactivity cyanide death decrease derivatization detection detector dose drug testing ecgonine ecgonine methyl ester effects electron elimination enzyme ethanol ethanol concentration excreted exposure extraction fects fenfluramine fluid fluorescence forensic toxicology g/dL gas chromatography GC/MS half-life HPLC hydroxylation immunoassay impairment increased ingestion inhalation injection ionization laboratory liver mass MDMA measured metabolism metabolites methamphetamine method mg/L mobile phase molecules morphine ng/mL occur opioids oral peak pharmacokinetic pharmacological phencyclidine phentermine plasma concentrations postmortem produce protein range reagent receptors sample screening seizures sensitivity serum smoking solvent specific specimens spectrometry studies substances technique temperature THCCOOH tion tissues tive toxic trations typically urine volatile