Residues of Some Veterinary Drugs in Animals and Foods: Monographs Prepared by the Fiftieth Meeting of the Joint FAO/WHO Expert Committee on Food Additives : Rome, 17-26 February 1998
Joint FAO/WHO Expert Committee on Food Additives. Meeting, Food and Agriculture Organization of the United Nations, World Health Organization
Food & Agriculture Org., 1999 - 145 páginas
This document is one of the three publications prepared by the fiftieth session of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), held in Rome in February 1998 and dedicated exclusively to the evaluation of veterinary during residues in food. The report of the meeting will be published in the WHO Technical Report Series, and the toxicological monographs as No. 41 in the WHO Food Additives Series. Residue monographs in this document provide information on chemical identity, properties, use, pharmacokinetics, metabolism and tissue residue depletion of, and analytical methods for, substances indicated on the cover. This publication is meant for regulatory authorities, veterinary drug researchers and any other concerned persons who wish to gain information and insights into the needs and problems involved in establishing maximum limits for veterinary drug residues in food.
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28 days administration analysis analytical method animals assay benzathine benzylpenicillin bioavailability bovine bovine somatotropin calves catde cattle Cmax days post dosing detection determined dexamethasone Drug Residues edible tissues eprinomectin evaluated excreted extraction faeces FAO/WHO Expert Committee febantel fenbendazole Food Additives gastrointestinal gentamicin goats HPLC HPLC method IGF-I injection sites IU/kg BW ivermectin JECFA Joint FAO/WHO Expert kidney lactating limit of quantification lincomycin liver LOQ LOQ marker residue maximum residue limits metabolism metabolites mg/kg on day mg/L microbiological moxidectin ng/ml nicarbazin oxfendazole sulfone parent drug penicillin pharmacokinetic phenylurea portion pigs plasma procaine benzylpenicillin radiolabeled Range Mean rats rbST rbST-treated cows recovery residue concentrations residue depletion study residues in milk residues in tissues sacrificed sarafloxacin SC injection sheep skin species spectinomycin spectinomycin residues Sponsor Submitted subcutaneous Table tissue residues total radioactive residues total residues turkeys ug/kg ug/L unlabeled urine veterinary drugs withdrawal