Pain in Peripheral Nerve Diseases, Volumen 13;Volumen 2001

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Claudia Sommer
Karger Medical and Scientific Publishers, 1 ene 2001 - 202 páginas
The book takes a novel approach to the subject of pain in peripheral nerve disease by bringing together basic scientists and clinicians with an expertise in the field of neuropathic pain. For the first time, the description of clinically relevant diseases, an up-to-date review of the pathophysiology of neuropathic pain and a comprehensive review of therapeutic options are combined in one book. Furthermore, the anatomy and pathology of peripheral nerve is outlined in the context of neuropathic pain. Peripheral nerve disorders causing pain, the mononeuropathies and polyneuropathies are described in detail including up-to-date summaries of pathogenesis and treatment. Two chapters elucidate the pathophysiology of neuropathic pain, one looking at causes in the periphery and one covering central mechanisms. Treatment options are outlined according to current knowledge from evidence-based medicine and a state-of-the-art treatment algorithm is given to facilitate practical management. Clinicians, neurologists and neurologists in training and basic scientists who are interested in pain will profit most from this book. Painful neuropathies are frequently encountered in clinical practice and are difficult to manage. The book helps to better understand and treat those conditions.
 

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Índice

Linkages between Clinical Observation and Discovery
1
Dorsal Root Ganglion
16
Clinical Characteristics of Neuropathic Pain
32
Complex Regional Pain Syndrome CPRS
38
Sciatic Nerve Lesions
44
References
51
Painful Hereditary Neuropathies
59
Chronic Inflammatory Demyelinating Polyradiculoneuropathy CIDP
65
Pain Mechanisms in Nerve Injury
109
Sensitization of Nerve Fibers
122
Sympathetic Sprouting in the Dorsal Root Ganglion DRG
134
Central Changes
149
AFiber Sprouting
155
Why Do Some Patients Develop Neuropathic Pain and Others Not?
168
Selective Serotonergic Reuptake Inhibitors SSRI
175
Neuroleptics
179

Borreliosis
71
Exotoxic Neuropathies
76
Painless Neuropathies with Selective LargeFiber Loss
89
Contributors
196
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