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the same person has had a near, and the other a distant sight.

It has been said by Dr. PORTERFIELD,* that the pupils of near sighted persons are more dilated than those of others. This, however, does not accord with the observations I have made in such cases.

It has also been commonly believed, that the size of the pupil is influenced by the distance of the object to which the attention is directed, this aperture being enlarged when the object is far off, and becoming more and more contracted as it is brought near. But though the activity of the fibres of the iris is sometimes sufficient to be visibly influenced by this circumstance, yet in the greater number even of those cases where the dilatation and contraction of the pupil are powerfully influenced by a difference in the strength of the light, the distance of the object, considered alone, produces so little effect upon it, as to be scarcely perceived. That it has, however, in general, some degree of power on the pupil is highly probable; and an extraordinary instance of this kind exists, at the present time, in a lady between thirty and forty years of age, the pupil of whose right eye, when she is not engaged in reading, or in working with her needle, is always dilated very nearly to the rim of the cornea; but whenever she looks at a small object, nine inches from the eye, it contracts, within less than a minute, to a size nearly as small as the head of a pin. Her left pupil is not affected like the right; but in every degree of light and distance, it is contracted rather more than is usual in other persons. The vision is not precisely alike in the two eyes; the right eye being in a small degree near * Treatise on the Eye and the Manner of Vision, Vol. II. p. 38.

sighted, and receiving assistance from the first number of a concave glass, whereas the left eye derives no benefit from it. This remarkable dilatation of the pupil of the right eye was first noticed about twenty years ago, and a variety of remedies have been employed at different times with a view to correct it; but none of them have made any alteration. It should be mentioned, that, in order to produce the contraction of the pupil, the object looked at must be placed exactly nine inches from the eye; and if it be brought nearer, it has no more power to produce the contraction than if it were placed at a remoter distance. It should also be mentioned, that the continuance of the contraction of the pupil depends, in some degree, on the state of the lady's health; since, though its contraction never remains long after the attention is withdrawn from a near object, yet whenever she is debilitated by a temporary ailment, the contraction is of much shorter duration than when her health is entire.*

Dr. WELLS, in his ingenious paper, published in the Second Part of the Transactions of the Royal Society for the year

• Several instances have come under my notice, in which the pupil of one eye has become dilated to a great degree, and has been incapable of contracting on an increase of light, whilst the pupil of the other eye has remained of its natural size. In some of these, the eye with the dilated pupil has been totally deprived of sight, the disorder answering to that of a perfect amaurosis; but in others, the dilatation of the pupil has only occasioned an inability to distinguish minute objects. Reading has been accomplished with difficulty, and convex glasses have afforded very little assistance. Though objects at a distance were seen with less inconvenience, than those that were near, these also appeared to the affected eye much less distinct than to the other. Most of the persons to whom I allude had been debilitated, by fatigue or anxiety, before the imperfection was discovered in the sight; and in some it had been preceded by affections of the stomach and alimentary canal.

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1811, has taken pains to ascertain, whether the power by which the eye is adjusted to see at different distances, depends in any degree on the faculty in the pupil of dilating and contracting; and whether its fixed dilatation has any influence in preventing an accurate view of near objects. This last mentioned effect Dr. WELLS relates to have taken place remarkably in the case of Dr. CUTTING, whose pupil being fixed in a dilated state by the action of the extract of belladonna, perfect vision of a near object was removed, as the dilatation advanced, from six inches (which was the nearest distance at which Dr. CUTTING could distinctly see the image of the flame of a candle reflected from the bulb of a small thermometer,) to seven inches in thirty minutes, and to three feet and a half in three quarters of an hour. My eldest son, who has a very extensive range of vision, has made a similar experiment on his right eye with a similar result. Previous to the application of the belladonna, he could bring the apparent lines on an optometer (like that improved by Dr. YOUNG from the invention of Dr. PORTERFIELD, and described in the Philosophical Transactions for the year 1800) to meet at four inches from the eye; and, by directing his attention to a more distant point, he could prevent them from meeting till they were seven inches from the eye, after which they continued apparently united the whole length of the optometer, which was twelve inches.* He could see the image of a candle

• The two lines that are perceived on looking through the slits of an optometer, cross each other precisely in the point from whence the rays of light diverge in order to be brought to a focus on the retina. And their apparent union before and after this point is occasioned by the unavoidable thickness of the line drawn on the optometer.

reflected from the bulb of a small thermometer, five-sixteenths of an inch in diameter, at the distance of three inches and three quarters from the eye; and he could also see the same image at the distance of two feet seven inches. The belladonna produced a conspicuous dilatation of the pupil in less than an hour; after which, on viewing the apparent lines on the optometer, he was unable to make them meet at a nearer distance than seven inches, or to gain a distinct image of the candle reflected by the bulb of the thermometer nearer than this distance; but he could discern it at two feet ten inches from the eye, which was three inches further than he was able to see it, before the belladonna was applied. During the time of the experiment on the right eye, the left eye possessed its usual range of vision, but the sight, when both eyes were open, was rather confused, in consequence of the unequal foci of the two eyes; and it did not become clear until the pupil of the right eye recovered its usual power of contracting, which power was not acquired till the third day after the application of the belladonna.

It is remarkable that a different effect is sometimes produced on a near sighted eye by the application of the belladonna, from that which it has on an eye that enjoys a distant sight. Dr. WELLS made an experiment of this kind on a friend of his, who was near sighted; and he informs us, in the paper above referred to, that in this instance, the nearest point of perfect vision was moved forwards during the dilatation of the pupil, whilst its remote point remained unaltered. I have made a similar experiment on the eyes of several such per-sons; and though in two of these the result appeared to be similar to that which has been mentioned by Dr. WELLS, yet,

in the greater number, their sight, like that of those who were not myopic, has become more distant as the pupil became more dilated. In one gentleman, in whom the lines of the optometer appeared to meet at four inches and a quarter from the eye, the pupil, in half an hour after the application of the belladonna, became completely dilated, and in consequence of this the sight at first was confused; but both on that day, and for two days afterwards, it was evidently more distant, and the apparent lines on the optometer could not be made to meet nearer than seven inches from the eye. In a young lady, seventeen years of age, whose right eye was so near sighted that the apparent lines on the optometer met at two inches and three quarters from the eye, these lines, when the pupil was dilated (which took place in a small degree in less than half an hour), could not be made to meet in less than three inches and a quarter; and on the following day, the pupil being more dilated, the lines did not meet till they were at the distance of nearly four inches.-In a third instance, viz. that of a lady forty-five years of age, who had been remarkably near sighted from her infancy, and for many years had used concave glasses of the fifteenth number, (which number is ground on each side, upon a tool the radius of which is only three inches,) the sight was become so confused in both eyes, that she saw nothing distinctly, and was unable to read letters, of the size that are used in the printed Transactions of the Royal Society, either with or without a glass. In this case, after the pupils had been dilated by the application of the belladonna, the sight was so much improved that she was able to read a print of the abovementioned size at the distance

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