Neuropsychology of HIV Infection, Número 494Igor Grant, Alex Martin Oxford University Press, 1994 - 385 páginas The human immunodeficiency virus (HIV) commonly enters the central nervous system, disturbs brain function, and ultimately results in serious brain damage. The most dangerous manifestation of this infection of the brain is HIV-associated dementia, which includes extreme memory loss, slowness in thinking, disorientation, and social incapacity. Most persons who are HIV-infected do not develop severe dementia; however, perhaps 50% of those with AIDS and a smaller proportion of HIV-infected carriers suffer from more subtle brain disorders that can be revealed by proper neuropsychological testing. This ground-breaking volume is the first to summarize the current state of knowledge about the neurocognitive disorders associated with HIV-1 infection. With contributions from leading authorities in the field, the book fully discusses the prevalence, qualitative features, natural course, and effects of neuropsychological impairments in persons with HIV infection. Neuropsychological data are related to findings from studies of brain imaging, neuropathology, and the effects of antiretroviral treatments. This critical work will be essential for neuropsychologists, infectious disease physicians, neurologists, and all those involved in AIDS research and treatment. |
Índice
INTRODUCTION | 3 |
CNSImmune Interactions | 41 |
Neurological and Neuropathological Manifestations of HIV Infection | 56 |
Structural Brain Imaging of HIV Infection | 108 |
Methodological and Conceptual Issues in the Study of Cognitive Change | 146 |
Computerized Testing to Assess Cognition in HIVPositive | 161 |
Development of a Screening Battery for HIVRelated Cognitive | 176 |
The Utility of Clinical Ratings for Detecting Cognitive Change in | 188 |
HIV Cognition and the Basal Ganglia | 234 |
Neuropsychological and Pathological | 260 |
Neuropsychological Response to Antiretroviral Therapy in | 276 |
A Clinical Perspective | 295 |
Developmental Deficits and Behavioral Change in Pediatric AIDS | 310 |
Motor and Cognitive Functioning in Nonhuman Primates Infected with | 339 |
EPILOGUE | 359 |
367 | |
Everyday Functioning and Its Relationship to Cognitive Impairment | 207 |
Neuropsychological Assessment of Seropositive Intravenous Drug | 220 |
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