Sepsis, Kidney and Multiple Organ Dysfunction: Proceedings of the Third International Course on Critical Care Nephrology, Vicenza, June 1-4, 2004Claudio Ronco, Rinaldo Bellomo, Alessandra Brendolan Karger Medical and Scientific Publishers, 1 ene 2004 - 403 páginas Severe sepsis is among the most common causes of death in the United States and the most common cause of death in the Intensive Care Units worldwide, and its recognition and treatment remain the most important challenges of critical care medicine. Severe sepsis and septic shock have a profound effect on kidney function and the function of other organs through complex mechanisms, which involve the immune response, multiple pro and anti-inflammatory pathways, intracellular dysfunction and hemodynamic instability. Their optimal management requires complex knowledge of general medicine, immunology, nephrology, extra-corporeal technology, fluid resuscitation and critical care endocrinology. In order to deliver optimal patient care, nephrologists and intensive care medicine specialists need to understand and be highly knowledgeable in the epidemiology of sepsis, the mechanisms of injury which determine outcome and the fundamental aspects of new insights into fluid resuscitation, acid-base physiology and glucose control. They also need to have a clear appreciation of new technical developments in the monitoring of critically ill patients and in the delivery of advanced extra-corporeal blood purification therapies.Experts from the fields of intensive care medicine, nephrology, endocrinology, acid-base physiology, extra-corporeal blood purification technology and immunology have contributed to the present book, providing a cutting edge view of developments in each field which contribute to the care of patients with severe sepsis, acute renal failure and multiple organ failure. The resulting mix of fundamental knowledge and recent developments from clinical trials and laboratory research constitute a valuable tool for all professionals involved in the care of the critically ill patient. |
Índice
Epidemiology and Pathogenesis of ARF Sepsis and MOF | 1 |
Pathological Mechanisms | 53 |
Fluid Electrolyte and Acid Base | 94 |
Pharmacological Issues in ARF and Sepsis | 158 |
Practical Aspects of CRRT | 191 |
Consensus and Recommendations from ADQI | 214 |
Which Treatment for ARF in ICU? | 239 |
Technical Aspects of CRRT | 291 |
CRRT Information Technology | 329 |
New Frontiers in the Management of ARF MOF and Sepsis | 350 |
395 | |
396 | |
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Términos y frases comunes
acid-base acidosis activation acute renal failure anticoagulation arterial associated Bellomo bicarbonate blood flow Blood Purif Brendolan cardiac catheter cells citrate Clin clinical concentration continuous renal replacement continuous venovenous Contrib Nephrol Crit critically ill patients CRRT CVVH CVVHD cytokines danaparoid decrease dose edema effect endotoxin extracorporeal factors flow rate fluid furosemide glucose hemodiafiltration hemodialysis hemodynamic hemofiltration heparin HVHF hyponatremia increased induced infection inflammatory response infusion injury insulin intensive care unit intermittent ischemia ischemic Karger Kidney Kidney Int Kt/V lactate levels loop diuretics mechanisms mediators membrane metabolic mg/dl mmol/l modalities molecules monocytes mortality Multiple Organ Dysfunction necrosis outcome patients with acute patients with ARF pediatric peritoneal dialysis Physiol plasma pressure protein pulmonary receptor removal renal function renal replacement therapy risk Ronco saline sepsis septic shock Soc Nephrol solutions survival syndrome treatment trial tubular ultrafiltration urea urea clearance vascular vasopressin venous ventilation volume