Advances in Clinical Chemistry, Volumen 40Gregory S. Makowski Gulf Professional Publishing, 28 nov 2005 - 424 páginas Volume forty in the internationally acclaimed Advances in Clinical Chemistry, contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics ranging from basic biochemical exploration to cutting edge microarray technology. In keeping with the tradition of the series, this volume emphasizes novel laboratory advances with application not only to both clinical laboratory diagnostics, but as well as practical basic science studies. This volume of Advances in Clinical Chemistry is an indispensable resource and practical guide for twenty-first century practitioners of clinical chemistry, molecular diagnostics, pathology, and clinical laboratory sciences in general. *Addresses biomarkers in heart disease and breast cancer *Presents the latest advances in real-time PCR with regard to clinical laboratory diagnostics *Written by international leaders in the field of clinical chemistry |
Índice
1 Abstract | xi |
3 Commercially Available Assays for BNP and NT proBNP | 7 |
4 BNP and NTproBNP as Markers of Heart Disease | 10 |
5 Conclusions | 24 |
References | 25 |
1 Abstract | 36 |
3 Oncosis | 37 |
4 Apoptosis | 48 |
5 Dicarbonyl Compounds | 190 |
6 AGE Peptides | 195 |
7 Trends to Be Expected | 211 |
Concept Variations and Data Analysis | 219 |
4 Real Time PCR Platforms | 226 |
5 Signal Detection Formats | 227 |
6 Design of Real Time PCR Assays | 231 |
7 Execution of RealTime PCR Assays | 236 |
5 Autophagy and Autophagic Cell Death | 62 |
6 Cell Death in Diseased Human Hearts | 77 |
7 Concluding Remarks | 81 |
References | 83 |
1 Abstract | 98 |
4 NonFDAApproved Biomarkers Currently Used in a Research Orientation | 108 |
5 Emerging Biomarkers | 111 |
References | 116 |
1 Abstract | 125 |
3 Standard Serological Repertoire | 127 |
4 Current Clinical Applications | 137 |
5 Pitfalls in the Serological Diagnosis | 139 |
6 Autoantibodies Under Investigation | 141 |
7 Supplemental Autoantibodies | 146 |
8 Summary | 149 |
References | 150 |
1 Abstract | 163 |
2 Introduction | 164 |
3 MALDI Mass Spectrometry of In Vitro Glycated Proteins | 166 |
4 MALDI Mass Spectrometry of In Vivo Glycated Proteins | 174 |
8 Applications of Real Time PCR | 238 |
9 Conclusions | 245 |
References | 247 |
1 Abstract | 259 |
3 Stages of Lung Development | 261 |
4 Transcriptional Control of Lung Development | 263 |
5 Growth Factors and Lung Development | 266 |
6 Summary | 295 |
Abbreviations | 296 |
References | 297 |
1 Abstract | 316 |
3 Male Reproductive System | 317 |
4 Gonadotropin Assays | 323 |
5 Fertilization | 325 |
6 Male Factor Subfertility | 327 |
7 Semen Analysis | 338 |
8 Environment and Male Reproductive Functions | 348 |
9 Conclusions | 351 |
Index | 363 |
Términos y frases comunes
abnormalities activity airway alveolar amplification analysis antibodies antigen apoptosis apoptotic assay autoantibodies autoimmune hepatitis autophagic autophagic cell death binding Biochem Biol brain natriuretic peptide branching morphogenesis breast cancer cardiac Cardiol cardiomyopathy caspases Cell Mol Chem chromosome chronic Clin clinical Czaja detection diabetic diagnosis differentiation dystrophin embryonic epithelial cells evaluation fibroblast fluorescence function gene expression genetic glucose glycation growth factor HbA1c heart failure Hepatology hormone human increased inhibition left ventricular levels liver disease lung development lung morphogenesis male markers membrane mesenchyme mice molecular molecules morphogenesis mRNA mutations myocardial infarction myocardium myocytes normal NT-proBNP nuclear nucleic acids oncosis oncotic pathway patients Physiol plasma polymerase primary biliary cirrhosis probes prognostic protein pulmonary quantitative reaction reactivity real-time PCR receptor regulation role samples semen serum signaling specific sperm cell subfertile syndrome target testosterone TGFß therapy tissue transcription tumor ubiquitin vascular VEGF vitro