Principles of Clinical PharmacologyArthur J. Atkinson Jr., Darrell R. Abernethy, Charles E. Daniels, Robert Dedrick, Sanford P. Markey Elsevier, 28 abr 2011 - 568 páginas This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists.
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Índice
| 1 | |
| 9 | |
DRUG METABOLISM AND TRANSPORT | 141 |
ASSESSMENT OF DRUG EFFECTS | 273 |
OPTIMIZING AND EVALUATING PATIENT THERAPHY | 323 |
DRUG DISCOVERY AND DEVELOPMENT | 421 |
APPENDIX I Abbreviated Tables of Laplace Transforms | 527 |
APPENDIX II Answers to Study Problems | 529 |
| 537 | |
Otras ediciones - Ver todo
Principles of Clinical Pharmacology Arthur J. Atkinson Jr.,Arthur J. Atkinson Vista previa restringida - 2001 |
Principles of Clinical Pharmacology Arthur J. Atkinson Jr.,Charles E. Daniels,Robert Dedrick,Charles V. Grudzinskas,Sanford P. Markey No hay ninguna vista previa disponible - 2001 |
Términos y frases comunes
absorption acid activity addition administration adverse agents analysis approach binding blood body cancer cause cells changes Chapter clearance Clin Pharmacol Ther clinical compartment compounds concentration decrease described determined differences digoxin disease distribution dose drug development effect elimination enzyme Equation errors estimate et al evaluation example expression factor Figure flow function gene half-life hepatic human identified important increased individuals infusion inhibition inhibitors initial interactions kinetics levels liver measured mechanism medication metabolism metabolites methods molecular needed normal observed occur oral organic P-glycoprotein parameters patients pharmacokinetics pharmacology Phase plasma population potential predicted pregnancy protein reactions receptor reduced relationship relative renal reported response result risk selection shown specific studies substrate Table therapeutic therapy tion tissue toxicity transport treated treatment trials tumor volume women
Pasajes populares
Página 7 - Pratt WB, Taylor P, eds. Principles of drug action: The basis of pharmacology. 3rd ed.
Referencias a este libro
Bioequivalence and Statistics in Clinical Pharmacology Scott D. Patterson,Byron Jones Vista previa restringida - 2005 |
Pharmaceutical Biotechnology: Fundamentals and Applications, Third Edition Daan J. A. Crommelin,Robert D. Sindelar,Bernd Meibohm No hay ninguna vista previa disponible - 2007 |