Stress-Inducible Cellular Responses

Portada
U. Feige, R.I. Morimoto, Barbara Polla
Birkhäuser, 11 mar 2013 - 495 páginas
This book will deal with heat shock proteins and more generally with stress-related inducible gene expression as a pleiotropic adaptive response to stress. It presents a textbook-like overview of the field not only to heat shock experts, but to physiologists, pharmacologists, physicians, neuropsychologists and others as well. It is intended to be a state-of-the-art and perspective book rather than an up-to-date presentation of recent data. It should provide a basis for new experimetal approaches to fields at the edge of the classical heat shock field. Drugs, UV irradiation and environmental toxics will be considered as important modulators of the stress response. Radical scavengers such as superoxide dismutases and inducible regulatory proteins of metallic ion status such as ferritin as well as immunophilins and protein disulfide isomerases will be considered within the frame of stress proteins. The potential practical applications of heat shock proteins in toxicology and medicine for the diagnosis, prognosis and eventually therapy of clinical conditions associated with an increased oxidative burden will be outlined. The role of heat shock proteins in the modulation of immune responses will also be included. The book considers heat shock from a broad perspective including fields for which heat-shock may become of importance in the very near future such as cellular responses to environmental stresses and complex stress responses under specific conditions. It was also felt timely to incorporate a whole section on medical and technological applications of stress proteins. The book will be invaluable for all those working on stress and is intended for every "stress laboratory" as a source of knowledge and perspectives.
 

Índice

Roles for hsp70 in protein translocation across membranes
25
J Wei and L M Hendershot
41
Sherman and A L Goldberg
57
W B Pratt U Gehring and D O Toft
79
Luz and W J Lennarz
96
Morimoto
119
Morimoto P E Kroeger and J J Cotto
138
T Yura K Nagahigashi and M Kanemori
165
Mammalian DNA repair responses and genomic instability
289
Z Zhu and D J Thiele
307
G H W Wong R L Kaspar and G Vehar
321
U Feige
335
U Feige and W van Eden
359
B S Polla and A Cossarizza
376
A Y C Liu Y K Lee D Manalo and L E Huang
393
Yahara
410

T A Rouault and R D Klausner
182
O Bensaude S Bellier M F Dubois F Giannoni
199
H Shinagawa
220
B S Polla
237
Tyrrell
255
N J Holbrook Y Liu and A J Fornace
272
Li and A Nussenzweig
425
K Suzue and R A Young
450
K Nagata
467
B S Polla
482
Página de créditos

Otras ediciones - Ver todo

Términos y frases comunes

Información bibliográfica