New Developments in Mutation Research

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Nova Publishers, 2007 - 272 páginas
Mutation refers to any change in the DNA of a cell. Mutations may be caused by mistakes during cell division, or they may be caused by exposure to DNA-damaging agents in the environment. Mutations can be harmful, beneficial, or have no effect. If they occur in cells that make eggs or sperm, they can be inherited; if mutations occur in other types of cells, they are not inherited. Certain mutations may lead to cancer or other diseases. This book gathers together and presents the latest research in this field.
 

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Índice

Germline and Somatic Mutations in Colorectal Cancers from Patients with Hereditary Nonpolyposis Colorectal Cancer
1
Mutations Induced by Polycyclic Aromatic Hydrocarbons
19
Progress in Mutation Research on the Tandem Repeat in the Genome
41
Progress in Transgenic Rodent Mutation Assays
71
The Role of Oxygen Free Radicals in DNA Damage and Mutation Induction
97
Translesion DNA Synthesis across Mono ADPribosylated Deoxyguanosine by Yfamily DNA Polymerases
133
DNA NonHomologous EndJoining in Unicellular Organisms
149
The Dominant Lethal Test in the Snail Biomphalaria Glabrata An Assay to Detection or Germ Cell Mutagens in Freshwater for Environmental Monito...
189
Dendrimers as Delivery Systems in Gene Therapy
217
DNA Oxidation and Alkylation in Diabetes
241
Index
257
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