Oncogenomics: Molecular Approaches to CancerCharles Brenner, David Duggan John Wiley & Sons, 19 nov 2004 - 400 páginas This book aims to assemble the only available rigorous, yet broadly accessible introduction to this new and exciting field. Oncogenomics: Molecular Approaches to Cancer is approachable by basic scientists, practitioners, and other health professionals required to familiarize themselves with the tremendous impact of genomics and proteomics on cancer research. Clearly written chapters offer reviews of state of the art topics such as molecular classification, early detection, SNPs in cancer, data mining, tissue microarrays, protein and antibody arrays, and drug targets. |
Índice
DNA RNA AND PROTEIN | 15 |
Section III MODEL SYSTEMS | 185 |
Section IV MOLECULARLY TARGETED DRUGS | 291 |
Section V CONCLUSION | 359 |
365 | |
Otras ediciones - Ver todo
Oncogenomics: Molecular Approaches to Cancer Charles Brenner,David Duggan No hay ninguna vista previa disponible - 2004 |
Términos y frases comunes
Acad Sci USA activity addition agents alleles alterations analysis approach array associated biological breast cancer c-Myc cancer cell Cancer Res carcinomas cause cDNA cell lines changes Chapter chromosome clinical clones cluster colorectal compared complex compounds copy number deletions detection disease drug effects et al factor familial Figure function gene expression genetic genomic growth human hybridization identification identify increased indicated individuals inhibition inhibitors intestinal involved kinase lead levels loss mapping mechanism methods mice microarrays molecular mouse multiple mutations Natl Acad Sci Nature normal oncogene pathway patients patterns phenotype polyp present Proc Natl profiling progression prostate protein proteomic receptor region regulation response risk role samples Science screening selected sequence showed signaling specific studies target technologies testing tissue transformation transgenic treatment trial tumor tumor suppressor types