Molecular Biology of the Toxic Response
Encouraging the incorporation of molecular biology techniques into the experimental approach to various toxicological problems, the format of the book is two-staged. Each chapter first introduces how various molecular techniques can be successfully applied to solving a specific toxicology question and proceeds to describe the techniques themselves. Also included is a discussion of the benefits and limitations of these techniques . This book will prove of value to practising researchers, but also to graduate students dealing with conceptual issues relating to molecular toxicology.
Comentarios de usuarios - Escribir una reseña
No hemos encontrado ninguna reseña en los sitios habituales.
Otras ediciones - Ver todo
Acad Sci USA acid activity addition adducts agents altered analysis animals ARNT assay associated binding Biochem Biol biomarkers cancer carcinogenesis carcinogens cells cellular changes characterized Chem chemicals cloned complex compounds containing cultures cytochrome damage demonstrated detected determined domain dose effects elements Environ environmental enzymes estrogen exposure factor Figure function gene expression genetic growth human identified important increased indicated induced inhibition interactions involved kinase levels ligands lines liver lung measured mechanism metabolism methods mice molecular mouse mRNA mutagenic mutations Natl Acad Sci Nature nuclear observed oxidative ozone pathway peroxisome Pharmacol phenotype polymorphism presence Proc Natl proliferation promoter protein recent receptor region regulation reporter gene resistance response role sequence shown signaling specific strains stress structure studies suggest TCDD tissues toxicity Toxicol transcription transgenic transgenic mice tumor vitro vivo