Molecular Virology: Molecular and Medical Aspects of Disease-Causing Viruses in Man and Animals

Portada
Springer Science & Business Media, 31 may. 1983 - 344 páginas
This book was written during a period when the technologies of genetic engineering were being applied to the study of animal viruses and when the organization and function of individual virus genes were being elucidated. This book, which uses human and animal viruses as models, aims to under stand the developments in molecular virology during the last 20 years. Al though molecular virology could also be taught by means of bacteriophages or plant viruses, the advantage of using animal viruses is in their ability to cause human and animal diseases as well as to transform cells, a primary problem in medicine. For the sake of clarity and convenience, not all the individual contributors to the various aspects of molecular virology were cited in the text. Instead, the reader is referred to review articles or key papers that list the numerous excel lent publications that have contributed to clarification of the various molecular processes. Thus the end-of-chapter bibliographies will guide the reader to the publications in which the original contributing authors are quoted. References given under the heading Recommended Reading are intended to assist those interested in pursuing a given subject further. I hope that this book will fulfill the purpose for which it is designed, and I urge readers to contact me if errors are found or updating is required.
 

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Índice

1 Steps in the development of virus research
3
2 Classification of viruses
16
3 Molecular considerations of virus replication and viruscell interactions
22
4 Genes in human cells determining virus susceptibility
32
VIRUS FAMILIES
35
Doublestranded DNA viruses
37
5 Poxviruses
39
6 Iridoviruses
54
bunyaviruses
179
Viruses with singlestranded RNA plus genomes
185
picomaviruses
187
togaviruses
203
coronaviruses
216
retroviruses RNA tumor viruses
220
Unclassified viruses
251
Marburg and Ebola viruses
253

7 Herpesviruses
59
8 Adenoviruses
88
9 Papovaviruses
103
10 Hepatitis B virus
122
Singlestranded DNA viruses
129
11 Paroviruses
131
RNA minus viruses
137
reoviruses
139
rhabdoviruses
144
paramyxoviruses
153
orthomyxoviruses
162
arenaviruses
175
Slow virus infections of the CNS
255
MEDICAL AND BIOLOGICAL CONSIDERATIONS
259
24 Immunization against virus diseases
261
epidemics
273
26 Antiviral drugs and chemotherapy of viral diseases of man
277
27 Laboratory diagnosis of diseasecausing viruses
306
28 Viruses and human cancer
313
29 Social economic and juridical aspects of virus diseases
317
IV SUMMARY
321
30 Summary
323
Index
333
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