Vogel and Motulsky's Human Genetics: Problems and ApproachesFriedrich Vogel, Gunter Vogel, Arno G. Motulsky, Departments of Medicine and Gerome Sciences Arno G Motulsky Springer Science & Business Media, 1997 - 851 páginas The fourth, completely revised edition of this classical reference and textbook presents a cohesive and up-to-date exposition of the concepts, results, and problems underlying theory and practice in human and medical genetics. In the 10 years since the appearance of the third edition, many new insights have emerged for understanding the genetic basis of development and function in human health and disease. Human genetics, with its emphasis on molecular concepts and techniques, has become a key discipline in medicine and the biomedical sciences. The fourth edition has been extensively expanded by new chapters on hot topics such as epigenetics, pharmacogenetics, gene therapy, cloning and genetic epidemiology. In addition a section giving an overview on the main model organisms (mouse, canine, dog, worm, fly, yeast) used in human genetics research has been introduced. This book will be of interest to human and medical geneticists, scientists in all biomedical sciences, physicians and epidemiologists, as well as to graduate and postgraduate students who desire to learn the fundamentals of this fascinating field. |
Comentarios de usuarios - Escribir una reseña
Índice
of Detrimental Mutations Impact of the Genetic Load Concept on Human | 1 |
History of Human Genetics | 11 |
Chromosomes | 25 |
3 | 53 |
Conclusions | 79 |
of Genes and Formal Genetics | 123 |
Modes of Inheritance | 129 |
4 | 135 |
Description and Dynamics | 495 |
13 | 501 |
Conclusions | 545 |
Conclusions | 580 |
14 | 615 |
Conclusions | 618 |
Research Strategies and Examples | 623 |
15 | 629 |
5 | 172 |
Conclusions | 191 |
6 | 229 |
Conclusions | 251 |
Genetic Diseases | 257 |
Symptoms Leading to the Detection of Enzyme Defects Clinical Diagnosis | 263 |
Prion Diseases | 352 |
8 | 361 |
Conclusions | 380 |
Do Thyroid Autoantibodies and Autoimmune Disease Also Enhance | 393 |
10 | 402 |
Somatic Mutation Cancer and Aging | 431 |
Conclusions | 454 |
11 | 464 |
16 | 693 |
Differences Between Populations | 705 |
18 | 706 |
Genetic Counseling and Prenatal Diagnosis Human Genome | 711 |
Genetic Manipulations and the Biological Future | 733 |
747 | |
Data Bases and Expert Systems | 757 |
Heritability Estimates from Twin Data | 769 |
Genetic Counseling | 775 |
Programs and Examples | 783 |
793 | |
807 | |