HLA and MHC: Genes, Molecules, and FunctionMichael J. Browning, Andrew J. McMichael BIOS Scientific Publishers, 1996 - 438 páginas This is a review of the major histocompatibility complex (MHC), and the role it plays in the immune response and in disease. The emphasis throughout is on the human MHC, but relevant animal studies are inclded to give a comprehensive review of the subject. |
Índice
Evolution of the major histocompatibility complex and MHClike | 1 |
Molecular genetics of HLA class I and class II regions | 23 |
The TAP and LMP genes | 30 |
Página de créditos | |
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Otras ediciones - Ver todo
Hla and Mhc: Genes, Molecules, and Function Michael Browning,Andrew McMichael No hay ninguna vista previa disponible - 1999 |
Términos y frases comunes
activation alleles amino acid analysis antibody antigen presentation arthritis associated autoimmune diseases binding Biol bound peptides calnexin CD4+ cell lines cell surface class I genes class I molecules class II region classical class complex class Cresswell CTL response cytotoxic T cells cytotoxic T lymphocytes domain DQB1 DRB1 encoded endosomal epitopes exon expression Figure function genetic genomic haplotypes heterodimer histocompatibility complex class HLA class HLA molecules HLA-A HLA-B HLA-DR human MHC identified immune response Immunogenetics Immunol Individual peptide sequencing induced infection interactions intracellular invariant chain ligands loci locus major histocompatibility complex McMichael MHC class MHC class II MHC molecules mice molecular motifs mouse mutation Natl Acad Nature nucleotide peptide-binding polymorphism Pool sequencing population Proc protein Rammensee receptor recombination regulation regulatory residues role selection specific Strominger JL structure studies superantigens susceptibility T-cell Tissue Antigens transcription factors transgenic transport Trowsdale virus vitro