Focus on Colorectal Cancer Research

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Julia D. Martinez
Nova Publishers, 2005 - 327 páginas
In Western countries, cancer of the large intestine and rectum (colorectal cancer) is the second most common type of cancer and the second leading cause of cancer death (after lung cancer). The incidence of colorectal cancer begins to rise at age 40 and peaks between ages 60 and 75. Cancer of the large intestine (colon cancer) is more common in women; rectal cancer is more common in men. About 5 percent of the people with colon or rectal cancer have more than one cancer of the colorectum at the same time. People with a family history of colon cancer have a higher risk of developing the cancer themselves. A family history of familial polyposis or a similar disease also increases the risk of colon cancer. People with ulcerative colitis or Crohn's disease have a higher risk of developing cancer. The risk is related to the person's age when the condition developed and the length of time the person has had the condition. Diet plays some role in the risk of colon cancer, but exactly how it affects risk is unknown. Throughout the world, people at highest risk tend to live in cities and eat a diet typical of affluent Westerners. Such a diet is low in fibre and high in animal protein, fats, and refined carbohydrates such as sugar. Risk seems to be reduced by a diet high in calcium, vitamin D, and vegetables such as brussel sprouts, cabbage, and broccoli.
 

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Índice

Molecular Pathogenesis of Colorectal Cancer Implications for Molecular Diagnosis
1
Protective Effect of Physical Activity on the Occurrence of Colorectal Cancer
25
Role of Phytochemicals in Colon Carcinogenesis
41
Colorectal Cancer and the Growth HormoneInsulinLike Growth FactorI Axis
65
Antitumour Activity of Yogurt
97
COX2 Prostaglandins and Colon Cancer
123
Early Colorectal Cancer New Diagnostic Methods and Colonoscopic Therapeutic Techniques
143
Treatment of Advanced Colorectal Cancer Current Status and Future Perspectives
171
Laparoscopic Surgery for Colon and Rectal Cancer
209
Development and Application of a New Trial Design for the Analysis of an Immune Modulator GCSF GranulocyteColony Stimulating Factor for Im...
241
Hereditary Colorectal Cancer
287
Index
323
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