Cancer of the Esophagus: Approaches to the Etiology

Portada
Cambridge University Press, 10 jun. 1993 - 282 páginas
The book deals briefly with the normal structure, functioning and biochemistry of the esophagus and with the histological and genetic changes accompanying the development of esophageal cancer in humans and animals. Factors implicated in causing esophageal cancer are described in relation to its very dramatic epidemiology. Thus dietary deficiencies and consumption of foods contaminated by Fusaria mycotoxins are discussed in connection with the extremely high incidence of the disease in certain sharply demarcated regions in China and South Africa, and alcohol and tobacco use are discussed in relation to the epidemiology in Europe and USA. Other hazards mentioned include opium in Iran, betel nut in Asia and bracken in Japan. The sole group of chemicals known to be very potent esophageal carcinogens in animal experiments, the nitrosamines, are described especially in terms of the widespread human exposure.
 

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Índice

Functioning of the esophagus
11
Precursor lesions and histopathology in experimental
27
Epidemiology
47
Exposure to Nnitroso compounds and risk assessment
84
Hazard presented by betal quid chewing
99
Alcoholic beverages and tobacco
117
Metabolism of ethanol and higher alcohols
137
Effect of ethanol and higher alcohols on basal cell
150
Tea
186
Molds and mycotoxins
221
Epidemiology and carcinogenicity
228
Fungal esophagitis
234
micronutrients fresh plant food
247
Possible mechanisms involved in carcinogenesis
272
Index
280
Página de créditos

phenolics tannins tea
170

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