Mast Cells in Allergic DiseasesHirohisa Saito, Yoshimichi Okayama Karger Medical and Scientific Publishers, 1 ene 2005 - 218 páginas In this book, the editors have focused on the roles of mast cells in allergic diseases and discuss the future direction of discovering drugs. Another implication of this book is to understand mast cells at the system level. System biology is a research category to understand biology at the system level by examining the structure and dynamics of cellular and organismal functions, rather than the characteristics of isolated parts of a cell or organism. |
Índice
Regulation of Mast Cell Development | 1 |
Regulation of Mast Cell Activation through FcepsilonRI | 22 |
Role of Oxidants in Mast Cell Activation | 32 |
Roles of Adaptor Molecules in Mast Cell Activation | 43 |
Receptors Regulation of Synthesis and Pathobiologic Implications | 59 |
Role of Mast Cell Proteases in Tissue Remodeling | 80 |
Mast Cell Mediators in Airway Remodeling | 85 |
Mast CellDerived Cytokine Expression Induced via Fc Receptors and TollLike Receptors | 101 |
Chemokine Receptor Expression by Mast Cells | 130 |
Mast Cell beta2Adrenoceptors | 145 |
Potential Role of Stem Cell Factor in the Asthma Control by Glucocorticoids | 154 |
Mast Cell Ion Channels | 163 |
Using Mast Cell KnockIn Mice to Analyze the Roles of Mast Cells in Allergic Responses in vivo | 179 |
Mast CellSpecific Genes New Drug Targets Pathogenesis | 198 |
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Términos y frases comunes
adaptor molecules agonists allergen Allergic Diseases allergic inflammation Allergy Clin Immunol anaphylaxis antigen asthma Austen KF basophils binding Biol Chem blood bronchial c-kit CCR1 CCR3 cell types Cells in Allergic channels chemokine receptors chymase Clin Invest cultured mast cells cysLTs cytokines cytosolic degranulation domain eicosanoids eosinophils fibroblasts Galli SJ glucocorticoids growth factor histamine human lung mast human mast cells human MCs IgE receptor IgE-dependent immune induce inflammatory inhibit intracellular ITAM leukotriene C4 levels ligand LTC4 lung mast cells mast cell activation mast cell survival mast cell-deficient mediators membrane Metcalfe DD mice mouse mRNA mucosal murine nasal Natl Acad Sci neutrophils NTAL pathway Pawankar PGD2 phosphorylation plasminogen activator inhibitor-1 potential production progenitors proliferation prostaglandin protein recruitment regulation release responses rhinitis roles of mast Saito H SH2 domain signaling skin smooth muscle ß2-adrenoceptor stem cell factor stimulation tion tissue transcripts tryptase upregulation vitro vivo wild-type
Pasajes populares
Página 160 - Besmer, P. (1990) The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus.