New Trends in Cancer for the 21st Century, Volumen 532

Portada
Antonio Llombart Bosch, Vicente Felipo
Springer Science & Business Media, 2003 - 293 páginas
Driving the Cell Cycle to Cancer.- Proliferation: The Cell Cycle.- Molecular Analysis of Gene Expression in Tumor Pathology.- Ewing Tumor Biology: Perspectives for Innovative Treatment Approaches.- Cancer Epigenetics: DNA Methylation and Chromatin Alterations in Human Cancer.- Molecular Analysis of Cancer Using DNA and Protein Microarrays.- Proteomic Approaches to the Diagnosis, Treatment, and Monitoring of Cancer.- Structural Basis of Tumoral Angiogenesis.- Matrix Metalloproteinases and Tumor Progression.- Angiogenesis Inhibitors and Their Therapeutic Potentials.- Mutated Tyrosine Kinases as Therapeutic Targets in Myeloid Leukemias.- Targeting PDGF Receptors in Cancer-Rationales and Proof of Concept Clinical Trials.- Immune-Promoted Tumor Cell Invasion and Metastasis. New considerations in cancer therapy.- Improvements of Survival in Nine Phase II Clinical Studies With Different Types of Cancer Upon Anti-Tumor Vaccination with an Autologous Tumor Cell Vaccine Modified by Virus Infection to Introduce Danger Signals.- Causation and Prevention of Solely Estrogen-Induced Oncogenesis: Similarities to Human Ductal Breast Cancer.- Cyclooxygenase-2 Inhibitors in Cancer Prevention and Treatment.- Exosomes for Immunotherapy of Cancer.- Breast Cancer Gene Expression Analysis ¡a The Case for Dynamic Profiling..- Development of the Epidermal Growth Factor Receptor Inhibitor TARCEVATm (OSI-774).- Gefitinib (TRESSA, ZD 1839) for Non-Small Cell Lung Cancer (NSCLC): Recents Results and Further Strategies.- Mechanism of Action of Anti-HER2 Monoclonal Antibodies: Scientific Update on Trastuzumab and 2C4.- EORTC Research and Development: Achievements and Future Perspectives.- Contributors.
 

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Índice

DRIVING THE CELL CYCLE TO CANCER
1
THE CELL CYCLE
2
PATHOLOGY
19
PERSPECTIVES FOR INNOVATIVE TREATMENT APPROACHES
27
DNA METHYLATION AND CHROMATIN ALTERATIONS IN HUMAN CANCER
39
MOLECULAR ANALYSIS OF CANCER USING DNA AND PROTEIN MICROARRAYS
51
PROTEOMIC APPROACHES TO THE DIAGNOSIS TREATMENT AND MONITORING OF CANCER
59
STRUCTURAL BASIS OF TUMORAL ANGIOGENESIS
69
IMPROVEMENTS OF SURVIVAL IN NINE PHASE II CLINICAL STUDIES WITH DIFFERENT TYPES OF CANCER UPON ANTI TUMOR VAC...
175
SIMILARITIES TO HUMAN DUCTAL BREAST CANCER
195
CYCLOOXYGENASE2 INHIBITORS IN CANCER PREVENTION AND TREATMENT
209
EXOSOMES FOR IMMUNOTHERAPY OF CANCER
215
BREAST CANCER GENE EXPRESSION ANALYSIS The Case For Dynamic Profiling
223
DEVELOPMENT OF THE EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITOR TARCEVA OSI774
235
REGENTS RESULTS AND FURTHER STRATEGIES
247
SCIENTIFIC UPDATE ON TRASTUZUMAB AND 2C4
253

MATRIX METALLOPROTEINASES AND TUMOR PROGRESSION
91
ANGIOGENESIS INHIBITORS AND THEIR THERAPEUTIC POTENTIALS
109
MUTATED TYROSINE KINASES AS THERAPEUTIC TARGETS IN MYELOID LEUKEMIAS
121
TARGETING PDGF RECEPTORS IN CANCER RATIONALES AND PROOF OF CONCEPT CLINICAL TRIALS
141
IMMUNEPROMOTED TUMOR CELL INVASION AND METASTASIS
153
ACHIEVEMENTS AND FUTURE PERSPECTIVES
269
CONTRIBUTORS
277
INDEX
283
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