Fibrogenesis: Cellular and Molecular BasisMohammed S. Razzaque Springer Science & Business Media, 7 ene 2005 - 216 páginas Fibrogenesis: Cellular and Molecular Basis is the first volume to provide a synopsis of the rapid progress that has been documented in fibrogenesis over last couple of years, which significantly enhanced our understanding of the pathomechanisms of fibrotic diseases. Knowledge on molecular and celluar basis of fibrotic diseases has provided opportunities to develop selective and effective gene-based therapeutic options. The chapters in this book have been selected to provide comprehensive information on fibrogenesis, which is not limited to any specific organ. Individual chapters present mechanisms of fibrotic diseases involving lung, liver, kidney, heart, blood vessels, and more. The relevance and significance of inflammatory cytokines, chemokines, transcriptional factors, fibrogenic molecules, signaling cascade, and matrix remodeling in fibrogenesis are explained in depth, providing the reader with current and updated information. |
Índice
Tissue Scarring Lessons from Wound Healing | |
Pathological Significance of Renal Expression of Proinflammatory Molecules | 7 |
Oxidative Stress Lipoproteins and Angiotensin II The Unholy Triad in the Pathogenesis of Renal Fibrosis | 24 |
Involvement of NFκB in Renal Inflammation and Sclerosis | 34 |
LowDensity Lipoprotein and Glomerulosclerosis | 41 |
Molecula Developments in the Treatment of Renal Fibrosis | 49 |
Myocardial Infarction and Cardiac Fibrogenesis | 65 |
Cardiac Fibrosis and Aging | 85 |
Matrix Remodeling and Atherosclerosis Effect of Age | 92 |
Molecular and Cellular Aspects of Liver Fibrosis | 106 |
Recent Therapeutic Developments in Hepatic Fibrosis | 110 |
Reversibility of Liver Fibrosis Role of Matrix Metalloproteinases | 131 |
Can Manipulation of Apoptotic Cell Death Benefit Tissue Scarring? | 148 |
Pulmonary Fibrogenesis The Role of Apoptosis and Its Clinical Potentials | 166 |
SilicaInduced Inflammatory Mediators and Pulmonary Fibrosis | 187 |
Otras ediciones - Ver todo
Fibrogenesis: Cellular and Molecular Basis Mohammed S. Razzaque No hay ninguna vista previa disponible - 2014 |