Leading Pharmaceutical Innovation: Trends and Drivers for Growth in the Pharmaceutical Industry ; with 20 Tables

Pharmaceutical giants have been doubling their investments in drug development, only to see new drug approvals to remain constant for the past decade. Driven by what is known the productivity dilemma in pharmaceutical innovation, many drug companies tried to hedge against risk exposure by resorting to defensive strategies such as mergers and acquisitions. This book investigates and highlights a set of proactive strategies, aimed at generating sustainable competitive advantage for its protagonists based on value-generating business practices.The authorsfocus on three sources of pharmaceutical innovation: new management methods in the drug development pipeline, new technologies as enablers for cutting-edge R&D, and new forms of internationalisation, such as outside-in innovation in the early phases of R&D. Our findings are illustrated in the case of the Swiss pharmaceutical industry, the leading exporter of pharmaceutical products in percentage of GDP, and some of its main pharmaceutical firms, such as Novartis and Hoffmann-La Roche. TOC:Challenges of Managing Pharmaceutical Innovation.- The Pharmaceutical Industry: Case Switzerland.- Technological Revolution: From Synthesis to Drug Engineering.- Strategic Management of the Drug Pipeline.- Internationalization of Pharmaceutical R&D.- Case Studies of Successful Practice.- Future Directions and Trends.