II. A course of Lectures and Demonstrations (one term) on SPECIAL PATHOLOGY, or a systematic study of the more important Diseases, with special reference to the organs and tissues affected, including the Blood and certain correlated tissues (Bone Marrow, Lymphoid Tissue, etc.), various Glandular Organs, and the structures of the Lymphatic, Circulatory, Respiratory, Alimentary, Urinary, Nervous, and Osseous Systems.

III. A course of PRACTICAL PATHOLOGY,* including BACTERIOLOGY and HEMATOLOGY (two terms). The work of the Practical Class consists of—

1. Practical training in some elementary histological methods.

2. A systematic study under the microscope and with the
naked eye of selected pathological lesions illustrative
of typical morbid processes and conditions described
under General and Special Pathology.

3. Laboratory instruction and demonstrations in general
bacteriological technique, including methods of steri-
lisation, preparation of culture media, methods of
isolation and of cultivation, methods of staining,
separation of bacterial products, inoculation, etc.
4. The systematic examination of the more important
bacteria concerned in disease, including their dis-
tinctive characters under the microscope and in culti-
vation, their localisation in the tissues, their mode of
action, etc., with special reference to clinical diag-
nosis. Some of the non-pathogenic bacteria may also
be examined.

5.-Practical instruction and demonstration in the
phenomena of immunity, with special reference to
the clinical applications of opsonins, agglutinins and
precipitins.

6. Practical instruction in methods of preparation, fixation, staining, and examination of blood films with special reference to clinical work.

N.B.-Microscopes for practical work in Bacteriology and Hæmatology require a suitable condenser, and a-inch homogeneous immersion objective. A triple dust-proof nose-piece will be found a great convenience. See regulations in reference to microscopes on pages 218-9.

See Regulation in reference to Microscopes on page 218.

IV. TROPICAL DISEASES.-Special attention is devoted, both in the lecture and in the practical courses, to the pathology of the more important forms of tropical disease.

V. CLINICAL PATHOLOGY AND POST-MORTEM EXAMINATIONS. -Students are urgently recommended to avail themselves of every opportunity that may be given in the pathological laboratory and theatre of the Royal Prince Alfred Hospital for the study of morbid anatomy, and the relation of clinical phenomena to morbid processes.

VI. POST-GRADUATE COURSES.-Special post-graduate courses will, from time to time, be announced.

ORIGINAL RESEARCH.-Original research in the subjects of Pathology and Bacteriology will be encouraged so far as the equipment and accommodation in the Laboratory will permit.

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Text Books.-For General Pathology, Greenfield and Lyon's "Chapters in Pathology,' or Coats's Manual of Pathology," or Sidney Martin's Manual of General Pathology." For Bacteriology, Muir and Ritchie's Manual of Bacteriology." For Hæmatology, Da Costa's "Clinical Hæmatology," or Cole's "Diseases of the Blood." For Special Pathology, Manson's Tropical Diseases,' "and either Osler's " Principles and Practice of Medicine," or Gibson's "Text Book of Medicine," or Clifford Allbutt's System of Medicine." The text-books by Thoma (translated by Bruce), by Hamilton, by Woodhead, and by Lazarus-Barlow, are also worthy of consultation.

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FOR STUDENTS OF DENTISTRY.

Students of Dentistry are required to attend the following

courses:

1. General Pathology (including Bacteriology) as prescribed for students of medicine.

2. Practical Pathology, as prescribed for students of medicine, in so far as it is illustrative of General Pathology, with, in addition, a short course on the special pathology and bacteriology of the mouth and teeth.

TEXT BOOK PRESCRIBED.-Greenfield and Lyon's "Chapters in Pathology;" Goadby's "Mycology of the Mouth."

51. MATERIA MEDICA AND THERAPEUTICS.

Mr. T. S. Dixson, M B., Ch.M.

(1) For Medical Students.

A course of 10 lectures on Posology, and another of 15 on Special Therapeutics, will be given to medical students in their fifth year.

(2) For Dental Students.

A course of 20 lectures on the Materia Medica and Therapeutics of the more important substances employed by Dentists, and adapted to the special requirements of the latter, will be given during Lent Term.

Text Books.-Materia Medica for Dentists, Gabell and Austin.

(3) For Pharmaceutical Students.

A course of lectures on Pharmaceutical Chemistry and Pharmaceutical Botany, treating primarily of the substances officinal, and secondarily of the more important substances not officinal in the British Pharmacopoeia, will be given to Pharmaceutical students. This course will consist of 50 lectures, and will be illustrated by diagrams, macroscopical and microscopical specimens, and such other means as may prove feasible.

Text Book.-Materia Medica, Greenish; British Pharmacopoeia with addendum.

For Reference.-Pharmacographia, Flückiger and Hanbury; Extra Pharmacopoeia, Martindale and Westcott; Pharmacopedia, White and Humphrey.

(The courses on Special Therapeutics and on Pharmaceutical Chemistry and Pharmaceutical Botany are optional for medical students.)

52.-PRINCIPLES AND PRACTICE OF MEDICINE.
W. Camac Wilkinson, B.A., M.D., Lond.

General observations upon Symptoms, objective and subjective. Variations of Temperature and of Pulse, and state of Tongue, Skin and Digestive Functions in Disease. Infection and Intoxication. Ptomaine Poisoning. Botulismus. Infection and Infectious Diseases.

A. Septicæmia. Sapræmia. Pyæmia. Erysipelas. Septic
Endocarditis. Acute Rheumatism. Furunculosis.
Carbuncle. Epidemic Cerebro-spinal Meningitis.
Influenza. Diphtheria. Tetanus. Typhoid Fever.
Malta Fever. Relapsing Fever. Cholera. Plague.
Tuberculosis. Leprosy. Actinomycosis and Madura
Foot. Syphilis. Glanders. Anthrax.
Hæmoglobinuric Fever. Measles. Scarlet Fever.
Malaria.
Typhus. Smallpox. Vaccinia. Chickenpox. Mumps.
Whooping Cough. Dengue. Yellow Fever. Tropical
Diseases. Rabies.

B. Parasitic Diseases. Hydatids.
Worms. General Diseases.

c. Diseases of Organs and Systems.

Intestinal and other

Text Books.—Osler's Medicine; Taylor's Medicine.

53.-TUTORIAL MEDICINE.

The Medical Tutor acts as an assistant to the Lecturers on Clinical Medicine, to whose courses of instruction the work of the Tutor is preparatory and supplementary. The meetings of the class are held at times suitable to the convenience of the students on the one hand, and to the arrangements of the hospital on the other hand. The class meets at least twice weekly during Term, and each meeting is of not less than one hour's duration. If need be, owing to the number of students in attendance, the class is subdivided so that each student may have as much individual attention as possible. A Class Examination is held at the end of each Term, and the results are communicated to the Registrar. The course is conducted on a definite and systematic plan, as directed from time to time by the Senate, and it is of an entirely practical nature. The Tutor seeks to make each student thoroughly acquainted with the signs of medical diseases, always comparing the abnormal with the normal, with the methods and means of medical diagnosis, and with the nature, use, and application of such instruments as are used in medical diagnosis and treatment. The Tutor also exercises a general superintendence over the work of the Clinical Clerks in the medical wards, and he gives them such assistance as they may require or properly recording the medical cases.

The outlines of the work of the class are somewhat as follows:

Special attention is paid to the proper way of taking the history of a medical case. Signs and symptoms, the difference, their significance.

METHODS OF EXAMINATION.-Inspection, palpation, percussion, auscultation, (a) the practice of these methods on the healthy, (b) the practice of the same methods on patients the subjects of disease, (c) the signs revealed by these methods in diseased conditions contrasted with the signs which obtain in health.

DIGESTIVE SYSTEM.-Examination of mouth and pharynx; inspection, palpation, and percussion of abdomen in health and in disease; examination of gastric contents, chemically; examination of material vomited, microscopically and chemically;

examination of fæces.

CIRCULATORY SYSTEM.-The pulse; its characters; the condition of the arteries; estimation of blood pressure; taking of sphygmograms and their interpretation. Venous pulse; its significance; examination of normal hearts; examination of diseased hearts; signs of dilatation and hypertrophy; normal heart sounds; abnormal heart sounds and their significance. The blood; estimation of corpuscles; estimation of hæmoglobin; the making of blood films.

RESPIRATORY SYSTEM.-Examination of normal chests by inspection, palpation, percussion and auscultation; types of breath sounds in healthy persons, and in patients subject of disease; characters of respiratory accompaniments.

URINARY SYSTEM.-Palpation of kidneys; examination of urine chemically, with special reference to urea, albumen, blood, bile and sugar; microscopical examination of urinary sediment.

NERVOUS SYSTEM.-The mental condition of the patient; examination of the cranial nerves, with reference to their functions; examination of motor functions with regard to paralysis, incoordination, abnormal movements; examination of sensory functions as to touch, temperature, pain, and muscle sense; examination of reflex functions; electric reactions of muscles and nerves.

54.-CLINICAL MEDICINE.

Dr. Scot-Skirving.

A, BEDSIDE INSTRUCTIONS IN THE WARDS OF THE PRINCE ALFRED HOSPITAL.- The methodical examination of patients, their symptoms and physical signs of disease. Discussion on the diagnosis and treatment of each case.

B. CLINICAL LECTURES on special cases, or on special subjects not otherwise dealt with or demonstrated at the bedside.