Fibrocytes: New Insights Into Tissue Repair and Systemic Fribrosis

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World Scientific, 2007 - 249 páginas
Since the discovery of the circulating ?fibrocyte? in 1994 as a collagen-producing cell of the peripheral blood, the physiologic and pathologic role of this unique cell populaton has grown steadily. This pioneering new book provides the first comprehensive review of the role of fibrocytes in wound repair, granuloma formation, antigen presentation, scar formation, and various fibrosing disorders such as interstitial lung disease and nephrogenic systemic fibrosis. It also includes discussions of the recent studies on the molecular signals that influence fibrocyte migration, proliferation, and function in the context of normal physiology and pathology. The chapters are contributed by the leading researchers in the field.
 

Índice

Discovery of a Circulating Connective Tissue Cell Progenitor Richard Bucala
1
Immunologic Features Jason Chesney
19
Chapter 3 Regulatory Pathways for Fibrocyte Differentiation Darrell Pilling and Richard H Gomer
37
Chapter 4 Hematopoietic Origin of Fibrocytes Amanda C LaRue and Makio Ogawa
61
Chapter 5 The Role of Fibrocytes in Postburn Hypertrophic Scarring JianFei Wang Yaujiong Wu Abelardo Medina Paul G Scott and Edward E Tred...
75
Chapter 6 Role in Asthmatic Lung Disease Sabrina Mattoli and Matthias Schmidt
105
Chapter 7 Fibrocytes and Other FibroblastMyofibroblast Progenitors in Systemic Sclerosis Arnold E Postlethwaite
125
Chapter 8 Fibrocytes in Interstitial Lung Disease Brigitte N Gomperts and Robert M Strieter
143
Chapter 9 Role of Fibrocytes in Renal Fibrosis Norihiko Sakai Takashi Wada Kouji Matsushima and Shuichi Kaneko
163
Chapter 10 Role of Fibrocytes in Atherogenesis Heather Medbury
175
A Prototype Fibrocyte Disease Cynthia L Kucher and Shawn E Cowper
195
Chapter 12 CD34+ Fibrocytes in Normal and Neoplastic Human Tissues Peter J Barth
227
Index
247
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