Drug Discovery: A History

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John Wiley & Sons, 23 jun. 2005 - 468 páginas
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Written by a leading authority with an excellent reputation and ability for writing a good narrative, Drug Discovery: A History is a far cry from simply a list of chemical structures.

This lively new text considers the origins, development and history of medicines that generate high media interest and have a huge social and economic impact on society.

Set within a wide historical, social and cultural context, it provides expanded coverage of pre-twentieth century drugs, the huge advances made in the twentieth century and the latest developments in drug research.

Hallmark features:

  • Up-to-the-minute information in drug research
  • Vignettes of special and unusual information, and anecdotes
  • Discusses drug prototypes from all sources
  • More comprehensive than other volumes on history of drug discovery

From the reviews:

"...an excellent bibliographic resource for those interested in the background papers that serve as the foundation for discovery of specific drug entities." JOURNAL OF MEDICAL CHEMISTRY, June 2006

"...a very comprehensive overview of drug development. It should be on the shelf on any aspiring pharmacist, medicinal chemist, or person interested in the history of therapeutic agents." JOURNAL OF CHEMICAL EDUCATION, February 2006

"...a very readable and closely researched book..." CHEMISTRY & INDUSTRY, October 2005

 

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Índice

PreHellenic Civilisations
12
Herbals
32
Systematic Medicine
74
DRUGS FROM NATURALLY OCCURRING PROTOTYPES
88
NonAlkaloidal Plant Products
106
BIOCHEMICALS
151
Peptide Hormones
164
Adrenal Cortex Hormones
179
DRUGS FROM MICROORGANISMS Chapter 22 Antibiotics
287
Antibiotic Analogues
319
Pharmacodynamic Agents from Microorganisms
341
Analogues of Pharmacodynamic Agents from Fungi
349
SYNTHETIC DRUGS Chapter 26 The First Synthetic Drugs and Their Analogues
355
Drugs Originating from the Screening of Dyes
375
Drugs Originating from the Screening of Organic Chemicals
403
Drugs Discovered through Serendipitous Observations Involving Humans
432

Prostaglandins
185
Hormone Analogues
188
Vitamins
226
Antimetabolites
248
Blood and Biological Products
269
Drugs Discovered through Serendipity in the Laboratory
438
Concluding Remarks
446
Index
448
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