Chemokines, Chemokine Receptors and Disease, Volumen 55Lisa M. Schwiebert Gulf Professional Publishing, 2 sept 2005 - 380 páginas This volume in the Current Topics in Membranes series discusses the biology of chemokines and their binding partners, chemokine receptors, in normal and disease-related states. Chemokines are small proteins that are important in normal immune responses. Recent research demonstrates a role for these proteins in a variety of diseases such as heart disease, allergy, asthma, and cancer. As a result of the discovery of this link to disease, the topic of chemokines and drugs that block their actions has become an intense are of study. This book presents the topics of chemokines, chemokine receptors, and related pathologies in an integrated manner that provides the reader with a comprehensive and up-to-date knowledge of these topics.
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Índice
Overview and History of Chemokines | 1 |
General Overview | 14 |
An Expanding Role for Chemokines | 21 |
The Biology of CXC Chemokines and Their Receptors | 49 |
The Biochemical Signal | 61 |
The Molecular and Cellular Biology of CC | 73 |
The Molecular and Cellular Biology of C and CX3C | 103 |
Future Directions and Unanswered Questions | 109 |
Chemokines in Adult CNS Function | 168 |
Chemokines and Chemokine Receptors | 189 |
Summary | 211 |
Chemokines Chemokine Receptors | 223 |
CXC Chemokines in Cancer | 255 |
NonELR+ CXC Chemokines Weaken Angiogenesis | 270 |
Evidence That Chemokines Regulate the Pattern | 277 |
Chemokines and Chemokine Receptors | 289 |
Chemokines and Their Receptors | 115 |
Chemokines and TCells | 123 |
Chemokines in Immune Surveillance | 143 |
Chemokines Have Direct Antimicrobial Effects | 150 |
Chemokines and Central Nervous System Physiology | 159 |
Viral Strategies to Circumvent | 305 |
Clinical Uses | 338 |
Discussion | 349 |
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Términos y frases comunes
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