Radiobiology for the Radiologist

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Lippincott Williams & Wilkins, 2006 - 546 páginas

The updated Sixth Edition of this popular text will remain the first choice for those who need current, clinically relevant information on how radiation affects the human body. Written by practicing, active radiobiologists, the book brings together basic laboratory research and practical, clinical applications. The easy-to-read text and informative illustrations ensure comprehension, and summaries at the end of each chapter facilitate quick review.

The first section covers topics applicable to diagnostic radiology, nuclear medicine, and radiation oncology; the second section offers material specifically for radiation oncologists. This edition includes new material about doses and risks in interventional radiology and cardiology.

 

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Índice

Milestones in the Radiation Sciences
1
Physics and Chemistry of Radiation Absorption
5
DNA Strand Breaks and Chromosomal Aberrations
16
Cell Survival Curves
30
Radiosensitivity and Cell Age in the Mitotic Cycle
47
Repair of Radiation Damage and the DoseRate Effect
60
Oxygen Effect and Reoxygenation
85
Linear Energy Transfer and Relative Biologic Effectiveness
106
Molecular Techniques in Radiobiology
240
Cancer Biology
274
DoseResponse Relationships for Model Normal Tissues
303
Clinical Response of Normal Tissues
327
Model Tumor Systems
349
Cell Tissue and Tumor Kinetics
363
Time Dose and Fractionation in Radiotherapy
378
Predictive Assays
398

Acute Effects of TotalBody Irradiation
117
Radioprotectors
129
Radiation Carcinogenesis
135
Hereditary Effects of Radiation
156
Effects of Radiation on the Embryo and Fetus
168
Radiation Cataractogenesis
181
Doses and Risks in Diagnostic Radiology Interventional Radiology and Cardiology and Nuclear Medicine
187
Radiation Protection
224
SECTION II
226
Alternative Radiation Modalities
407
Radiosensitizers and Bioreductive Drugs
419
Gene Therapy
432
Chemotherapeutic Agents from the Perspective of the Radiation Biologist
440
Hyperthermia
469
Glossary
491
Index
521
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