Flow Cytometry and Immunohistochemistry for Hematologic Neoplasms

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Lippincott Williams & Wilkins, 2008 - 335 páginas

This text is a detailed guide to the use of flow cytometry, immunohistochemistry, and molecular genetic techniques for diagnosis of hematologic neoplasms. Dr. Sun explains the principles of these techniques and demonstrates their utility in 39 clinical cases covering all important entities. Each case represents a comprehensive diagnostic approach including a clinical history and flow cytometric, immunohistochemical, and molecular genetic findings.

Abundant full-color illustrations show histologic sections, immunohistochemical stains, bone marrow, peripheral blood, and body fluid smears, and each case includes a complete set of flow cytometric histograms. Over 100 tables compare and differentiate the diagnostic features of similar diseases.

An image bank will be available on a companion Website.

 

Índice

General Introduction
1
Principles of Flow Cytometry
4
Principles of Immunohistochemistry
15
Molecular Genetics
24
Classification of Hematologic Neoplasms
35
Clinical Application
45
Chronic Myelogenous Leukemia
52
Myelodysplastic Syndromes
60
Prolymphocytic Leukemia
172
Lymphoplasmacytic Lymphoma
178
Plasma Cell Myeloma and Plasmacytoma
185
Hairy Cell Leukemia
196
Splenic Marginal Zone Lymphoma
204
Extranodal Marginal Zone BCell Lymphoma
210
Nodal Marginal Zone BCell Lymphoma
218
Follicular Lymphoma
223

MyelodysplasticMyeloproliferative Diseases
69
Acute Myeloid Leukemia with t821q22q22
79
Acute Myeloid Leukemia with inv16p13q22 or t1616p13q22
81
Acute Promyelocytic Leukemia with t1517
86
Acute Myeloblastic Leukemia without Maturation
92
Acute Myeloblastic Leukemia with Maturation
101
Acute Myelomonocytic Leukemia
105
Acute Monoblastic and Monocytic Leukemia M5 and
110
Acute Erythroid Leukemia
116
Acute Megakaryoblastic Leukemia
122
Myeloid Sarcoma
129
Precursor BLymphoblastic LeukemiaLymphoma
136
Precursor TLymphoblastic LeukemiaLymphoma
143
Chronic Lymphocytic Leukemia of BCell Lineage
152
Chronic Lymphocytic Leukemia of TCell Lineage
160
Small Lymphocytic Lymphoma
165
Mantle Cell Lymphoma
232
Diffuse Large BCell Lymphoma
241
Mediastinal Thymic Large BCell Lymphoma
247
Burkitt LymphomaLeukemia
253
TCell Large Granular Lymphocyte Leukemia
261
Natural Killer Cell Lymphoma
267
Adult TCell LeukemiaLymphoma
277
Hepatosplenic TCell Lymphoma
284
Mycosis Fungoides and Sézary Syndrome
289
Peripheral TCell Lymphoma Unspecified
297
Anaplastic Large Cell Lymphoma
304
Hodgkin Lymphoma
312
Thymoma
322
Index
329
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