Oxidative Stress in Cancer, AIDS, and Neurodegenerative DiseasesCRC Press, 6 oct 1997 - 576 páginas Based on a conference on Oxidative Stress and Redox Regulation, held at the Pasteur Institute, Paris, this work examines fundamental, chemical, biological and medical studies of free radicals on different targets and the consequences of their reactivity. It covers the chemistry and biochemistry of free radicals, free radicals as second messengers that group the activation of transcription factors and enzymes, the importance of the antioxidant system in cell metabolism regulation, and the role of free radicals and antioxidants in disease management. The editors of this work are three of the most respected pioneers in the field. Dr. Montagnier is credited as the discoverer of HIV. |
Índice
The Importance of OxidantAntioxidant Balance | 3 |
The Effect of Oxidative Stress on Cells by Oxygen Radicals and Its Inhibition by Antioxidants | 11 |
Cytotoxicity of RadiationDerived Reactive Oxygen Species | 17 |
Regulation of the Bacterial Response to Hydrogen Peroxide | 31 |
Activation of Lymphocyte Signal Pathways by Oxidative Stress Role of Tyrosine Kinases and Phosphatases | 37 |
Oxidantmediated Modulation of Phospholipases in Endothelial Cells Possible Implication in Vascular Disorders | 47 |
NFkB Transcription Factor Activation Importance of the Redox Regulation | 65 |
Redox Regulation of the NFkB Signaling Pathway and Disease Control | 77 |
Flavonoid Functions In Vivo Are They Predominantly Antioxidants? | 287 |
Immunoregulatory Properties of Superoxide Dismutase | 307 |
Pharmacological Inhibition of Endothelial Cytoskeleton Alterations Induced by Hydrogen Peroxide and TNF𝛼 | 315 |
Perinatal Development of Superoxide Dismutase and Other Antioxidant Enzyme Activities in Ratbrain Mitochondria | 325 |
Coexistence of a Reactive Oxygen Cycle with QCycle and H+Cycle in the Respiratory Chain A Hypothesis for the Generation Partitioning Targeting a... | 335 |
Endogenous Oxidative DNA Damage and Spontaneous Mutagenesis Role of 8Oxoguanine | 353 |
The Elevated Serum Level of Thioredoxin in Patients with Malignant Disease and Chronic Inflammatory Diseases | 361 |
The Role of Free Radicals in Antitumor Effects of Cancer Treatments | 371 |
Mechanism of Activation of NFkB by Hydrogen Peroxide | 85 |
Selfregulation of the NFkBlkB𝛼 System and Its Positive and Negative Control by the Cellular Redox Status | 91 |
The Role of Hydrogen Peroxide in Signal Transduction and the Involvement of Iron | 99 |
Redox Regulation of Heat Shock Protein Expression and Protective Effects Against Oxidative Stress | 115 |
LowDensity Lipoproteins Modulate Nitric Oxide and Heme Oxygenase Signal Transduction Pathways in Vascular Endothelium and Smooth Muscle | 129 |
Nitric Oxidestimulated Tyrosine Phosphorylationdependent Signaling Pathways in Cultured Cells | 141 |
Regulation of Cell Activation by Receptors for IgG | 149 |
Signal Transduction Pathways Activated by Mitogenic Neuropeptides | 165 |
Glutathione Metabolism During Apoptosis | 181 |
Endogenously Generated Superoxide and Hydrogen Peroxide in the Redox Modulation of Cell Proliferation Apoptosis and Virus Replication | 193 |
DeoxyDRiboselnduced GSH Depletion and Induction of Apoptosis in Human Quiescent Peripheral Blood Mononuclear Cells Effects of NAcetylcyste... | 201 |
Nitric Oxide and Hydrogen Peroxide Production during Apoptosis of Human Neutrophils | 207 |
The Mitochondrion as a SensorEffector of Oxidative Stress During Apoptosis | 215 |
Antioxidants and the Regulation of Reactive Iron | 225 |
Redox Regulation by the Thioredoxin and Glutaredoxin Systems | 231 |
ThioredoxinAdult T Cell LeukemiaDerived Factor as the Key Redox Regulator of Signaling | 249 |
Therapeutic Potential of the Antioxidant and Redox Properties of 𝛼Lipoic Acid | 253 |
Glutathione Compartmentation and Oxidative Stress | 271 |
The Role of Cysteine and Glutathione in the Pathogenesis of HIV Infection Effects of Treatment with NAcetylcysteine | 375 |
Low Glutathione Levels in CD4 T Cells Predict Poor Survival in AIDS NAcetylcysteine May Improve Survival | 381 |
Modulation of HIV1 Long Terminal Repeat by Arachidonic Acid | 391 |
Protein Degradation in Lymphocytes as an Indicator of Oxidative Stress in HIV Infection | 401 |
Oxidative Stress and AIDS Oneyear Supplementation of HIVpositive Patients with Selenium or 𝛃Carotene | 411 |
Glutathione Oxidation and Mitochondrial DNA Damage in AIDS Effect of Zidovudine | 431 |
Effect of LCarnitine Treatment In Vivo on Apoptosis and Ceramide Generation by Peripheral Blood Lymphocytes from AIDS Patients | 439 |
Nutriceutical Modulation of Glutathione with a Humanized Native Milk Serum Protein Isolate IMMUNOCAL Application in AIDS and Cancer | 449 |
Successful Antioxidant Therapy Including Superoxide Dismutase Associated with Antiretroviral Therapy in an HIVInfected Patient with Hepatitis Bre... | 465 |
Parkinsons Disease Apoptosis and Oxidative Stress | 471 |
Protein Oxidation and Glycation in Neurodegenerative Diseases | 487 |
Glycation as Oxidative Stress and Redox Regulation Implications for Aging Diabetes and Familial Amyotrophic Lateral Sclerosis | 499 |
Oxidative Stress in IschemiaReperfusion Reillys Irritation Syndrome Revisited | 505 |
Evaluation of the Antiperoxidase Defense System of the Lens Utilizing GSH Peroxidase Transgenics and Knockouts | 509 |
The Rheumatoid Joint RedoxParadox? | 519 |
Chronic Oxidative Stress in Rheumatoid Arthritis Implications for T Cell Function | 539 |
549 | |
Otras ediciones - Ver todo
Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases Luc Montagnier,Rene Olivier,Catherine Pasquier Vista previa restringida - 1997 |
Oxidative Stress in Cancer, AIDS, and Neurodegenerative Diseases Luc Montagnier,Rene Olivier,Catherine Pasquier No hay ninguna vista previa disponible - 1997 |
Oxidative Stress in Cancer, Aids, and Neurodegenerative Diseases Luc Montagnier,Rene Olivier,Catherine Pasquier No hay ninguna vista previa disponible - 2019 |
Términos y frases comunes
Acad Sci USA acid activation antibody antioxidant apoptosis apoptotic binding Biol Chem bombesin Ca2+ Cancer catalase cell death cellular Clin coli concentrations cysteine cytokines cytotoxicity damage decrease disulfide effects endothelial cells enzyme expression FcyRIIB Figure flavonoids free radicals function gene glutaredoxin growth factor GSH levels GSSG Herzenberg HIV infection human hydrogen peroxide Immunol increase incubation induced inhibition inhibitor intracellular involved lipid peroxidation lipoate lymphocytes mechanism mediated membrane metabolism mitochondrial modulation molecular molecules NADPH Natl Acad Sci neurons NFKB ng/ml nitric oxide nuclear oxidative stress Parkinson's disease pathway patients phosphorylation plasma Proc Natl Acad production protein kinase reaction reactive oxygen species receptor redox redox regulation reduced response rheumatoid role selenium serum signal transduction specific stimulation studies substrate subunit superoxide dismutase synthesis thiol thioredoxin reductase tissue TNF-a transcription factor treatment tumor tyrosine kinase tyrosine phosphorylation virus vitamin vitro vivo
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